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NF45 (ILF2, nuclear factor of activated T cells 45 kDa) is a transcription factor that interacts with NF90 (ILF3, DRBP76) to regulate gene expression. NF45 and NF90 are proteins that belong to the double-stranded RNA-binding protein family and both are substrates for the dsRNA-activated protein kinase, PKR. The NF45/NF90 heterodimer is mainly involved in regulating IL-2 expression by binding to the antigen receptor response element (ARRE) target sequence of the IL-2 enhancer. In neuronal cells, the NF45/NF90 heterodimer can repress human rhinovirus type 2 replication by binding to a 5' untranslated region of the viral RNA that encodes the internal ribosome entry site (IRES).
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps NF45 (A-8) | sc-271718 | 200 µg/ml | $316.00 | |||
NF45 (A-8): m-IgG Fc BP-HRP Kit | sc-537687 | 200 µg Ab; 10 µg BP | $354.00 | |||
NF45 (A-8): m-IgGκ BP-HRP Kit | sc-535033 | 200 µg Ab; 40 µg BP | $354.00 | |||
NF45 (A-8): m-IgG1 BP-HRP Kit | sc-545307 | 200 µg Ab; 20 µg BP | $354.00 |