Neisseria meningitidis Antibody (6171): sc-69940

Neisseria meningitidis Antibody (6171) is a mouse monoclonal IgG antibody that detects Neisseria meningitidis in bacterial samples by immunofluorescence (IF). Neisseria meningitidis is a Gram-negative bacterium that resides in the nasopharyngeal tract of humans and causes epidemic bacterial meningitis. This bacterium features a unique polysaccharide capsule that plays a crucial role in pathogenicity by evading host immune responses. The capsular polysaccharide inhibits T-independent immune responses, which are essential for long-term immunity, by preventing memory cell formation and antibody affinity maturation. This evasion strategy allows Neisseria meningitidis to persist in hosts and increases the risk of severe disease, including rapid progression from initial symptoms like fever and headache to life-threatening conditions such as coma and death. With a mortality rate of approximately 10% among affected individuals, Neisseria meningitidis infection requires immediate medical attention, especially in immunocompromised patients or those with close contact to carriers. Anti-Neisseria meningitidis antibody (6171) enables researchers to visualize and analyze bacterial presence in biological samples.