Anticorps MTHFD1L (6C7): sc-100783
- L'Anticorps MTHFD1L (6C7) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 50 µg/0.5 ml
- dirigé contre la MTHFD1L recombinante d'origine human
- recommandé pour la détection de MTHFD1L d'origine mouse, rat et human par WB, IP et ELISA
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire MTHFD1L (6C7). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
ACCÈS RAPIDE AUX LIENS
Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) is a 935-amino acid, folate-dependent protein that is responsible for the consecutive interconversion of tetrahydrofolate derivatives which drive the synthesis of purine, methionine and thymidylate. MTHFD1 functions as a homodimer consisting of two major domains; an N-terminal domain containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain in the C-terminus. Mutations in the MTHFD1 gene in pregnant women are associated with an increased risk of giving birth to a child with a neural tube defect, along with a possible risk of decreased embryo survival. MTHFD1L (methylenetetrahydrofolate dehydrogenase 1-like) is a 978 amino acid mitochondrial protein that is expressed in a variety of tissues and, like MTHFD1, functions in folate metabolism via the tetrahydrofolate pathway. MTHFD1L exists as two isoforms and may be associated with colorectal carcinogenesis, possibly conferring a growth advantage to cancer-transformed cells.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps MTHFD1L (6C7) | sc-100783 | 50 µg/0.5 ml | $333.00 |