Date published: 2025-9-8

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Anticorps MAP-2 (B-8): sc-74420

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Fiches techniques
  • L'Anticorps MAP-2 (B-8) est un monoclonal de souris IgG1 κ, cité dans 6 publications, fourni en 200 µg/ml
  • dirigé contre les acides aminés 1-300 de MAP-2 d'origine human
  • recommandé pour la détection de MAP-2 d'origine human par WB, IP, IF, IHC(P) et ELISA
  • Voir MAP-2 (A-4): sc-74421 pour d'autres anticorps conjugués MAP-2, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
  • m-IgG Fc BP-HRP et m-IgG1 BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps MAP-2 (B-8) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps MAP-2 (B-8) (voir Informations pour la commande ci-dessous).

ACCÈS RAPIDE AUX LIENS

VOIR ÉGALEMENT...

Microtubules, the primary component of the cytoskeletal network, interact with proteins called microtubule-associated proteins (MAPs). The microtubule-associated proteins can be divided into two groups, structural and dynamic. The structural microtubule-associated proteins, MAP-1A, MAP-1B, MAP-2A, MAP-2B and MAP-2C, stimulate tubulin assembly, enhance micro-tubule stability and influence the spatial distribution of microtubules within cells. Both MAP-1 and, to a greater extent, MAP-2 have been implicated as agents of microtubule depolymerization by suppressing the dynamic instability of the microtubules. The suppression of microtubule dynamic instability by the MAP proteins is thought to be associated with phosphorylation of the MAPs.

Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

Informations pour la commande

Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

Anticorps MAP-2 (B-8)

sc-74420
200 µg/ml
$316.00

MAP-2 (B-8): m-IgG Fc BP-HRP Kit

sc-539516
200 µg Ab; 10 µg BP
$354.00

MAP-2 (B-8): m-IgG1 BP-HRP Kit

sc-541537
200 µg Ab; 20 µg BP
$354.00

How specific is the reactivity of this antibody for human MAP2 protein? And is there any data for cross-reactivity with mouse and rat tissue? Would like to use it to identify human xenograft in mouse spinal cord.

Posée par: xtensibleMlanguage
Thank you for your question. MAP-2 Antibody (B-8): sc-74420 is only recommended for detection of MAP-2 of human origin by WB, IP, IF, IHC(P) and ELISA. There is data for this antibody in murine cerebral cortices and there may be cross-reactivity with rat samples in different tissues as well.
Répondue par: Tech Support Europe
Date de publication: 2021-01-13

Can MAP-2 (B-8): sc-74420 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Posée par: Trav11
Thank you for your question. Yes, MAP-2 (B-8): sc-74420 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Répondue par: Technical Support
Date de publication: 2017-02-28
  • y_2025, m_8, d_29, h_8CST
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Rated 5 de 5 de par Positive band in WB in IMRPositive band in WB in IMR-32 whole cell lysates. -SCBT QC
Date de publication: 2015-01-12
Rated 5 de 5 de par Exceptional immunoperoxidase neuropil andExceptional immunoperoxidase neuropil and cytoplasmic staining in formalin fixed, paraffin-embedded human brain tissue. -SCBT QC
Date de publication: 2015-01-08
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Anticorps MAP-2 (B-8) est évalué 5.0 de 5 de 2.
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