Anticorps Ly-6D (RGRSL 114.8.1): sc-65885
- L'anticorps Ly-6D RGRSL 114.8.1 est un monoclonal IgG2a de rat fourni en 200 µg/ml
- dirigé contre Ly-6D d'origine mouse
- recommandé pour la détection de Ly-6D d'originie mouse par FCM
- disponible conjugué soit à la phycoérythrine soit à la FITC pour IF, IHC(P) et FCM
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire Ly-6D (RGRSL 114.8.1). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
Ly-6D (Lymphocyte antigen 6D), also known as E48 antigen, is a 128 amino acid glycoprotein that is expressed in squamous cell carcinoma cell lines and squamous cell epithelia tissue. Ly-6D contains a signal peptide, 2 theoretical phosphorylation sites and 3 putative myristoylation sites. Upregulation of the gene encoding Ly-6D in head and neck cancers is associated with poor prognosis and high expression of Ly-6D has been linked to enhanced cell migration. Ly-6D is frequently used as a molecular marker for diagnosis and therapy of head-and-neck squamous cell carcinoma (HNSCC). It has been suggested that Ly-6D may regulate the expression levels of certain fucosylated E-selectin ligands and protein FX, a protein that contributes to the last step in the synthesis of GDP-L-fucose, in HNSCC cell lines. This finding is indicative that Ly-6D may regulate tumor cell adhesion in inflamed vessel walls that express E-selectin.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Ly-6D (RGRSL 114.8.1) | sc-65885 | 200 µg/ml | $316.00 | |||
Anticorps Ly-6D (RGRSL 114.8.1) FITC | sc-65885 FITC | 200 µg/ml | $330.00 | |||
Anticorps Ly-6D (RGRSL 114.8.1) PE | sc-65885 PE | 200 µg/ml | $343.00 |