Kinesin is a cytoskeletal motor protein involved in axonal transport and cell division. The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule- and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination, and speed of transportation of a variety of important functional molecules, including mRNA. KIFs are involved in neuronal function and development. Kinesin family member 12 (KIF12) is a kinesin-like 651-amino-acid protein which is involved in mitotically linked cytokinesis. KIF12 is required during mitosis for normal myosin II localization and during late anaphase and telophase for normal nuclear separation. The KIF12 gene consists of a KISc domain, a coiled-coil domain with an internal hinge region and a C-terminal tail domain. KIF12 mRNA is expressed in fetal liver, adult brain, pancreatic islet, kidney tumors, and uterine and pancreatic cancers.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps KIF12 (A-9) | sc-376766 | 200 µg/ml | $316.00 | |||
KIF12 (A-9): m-IgG Fc BP-HRP Kit | sc-540641 | 200 µg Ab; 10 µg BP | $354.00 | |||
KIF12 (A-9): m-IgG2a BP-HRP Kit | sc-546942 | 200 µg Ab; 10 µg BP | $354.00 |