IDH3A (Isocitrate dehydrogenase [NAD] subunit a (mitochondrial), NAD(+)-specific ICDH) is a 366 amino acid protein encoded by the human gene IDH3A. IDH3A belongs to the isocitrate and isopropylmalate dehydrogenases family and can bind one magnesium or manganese ion per subunit. It is usually found in the mitochondrion as a heterooligomer of subunits a, b, and g in the apparent ratio of 2:1:1. Human NAD-dependent isocitrate dehydrogenase (IDH) is allosterically activated by ADP by lowering the Km for isocitrate. NAD-dependent isocitrate dehydrogenase is a tricarboxylic acid cycle enzyme that produces 2-oxoglutarate, an organic acid required by the glutamine synthetase/glutamate synthase cycle to assimilate ammonium.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps IDH3A (B-7) | sc-514358 | 200 µg/ml | $316.00 | |||
IDH3A (B-7) peptide neutralisant | sc-514358 P | 100 µg/0.5 ml | $68.00 |