Anticorps HYAL1 (4F9): sc-101341
- L'Anticorps HYAL1 (4F9) est un monoclonal de souris mouse IgG1 κ (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 1-366 de HYAL1 d'origine human
- recommandé pour la détection de amino acids 330-634 of HYAL1 d'origine mouse, rat, human et hamster par WB et IP; non cross-reactif avec HYAL2 or HYAL3
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire HYAL1 (4F9). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
ACCÈS RAPIDE AUX LIENS
Hyaluronidases (HAases or HYALs) are a family of lysosomal enzymes that are crucial for the spread of bacterial infections and of toxins present in a variety of venoms. HYALs may also be involved in the progression of cancer. In humans, six HYAL proteins have been identified. Most HYAL proteins degrade hyaluronic acid (HA), which is present in body fluids, tissues and the extracellular matrix of vertebrate tissues. HA keeps tissues hydrated, maintains osmotic balance and promotes cell proliferation, differentiation and metastasis. HA is also an important structural component of cartilage and other tissues and acts as a lubricant in joints. HYAL1 is a 435 amino acid hyaluronidase that is is expressed in multiple tissues, specifically in the serum, and is not expressed in brain. HYAL1 degrades HA into into fragments that stimulate angiogenesis. Expression of HYAL1 in various cancer cells may have a role in the regulation of tumor growth and progression.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps HYAL1 (4F9) | sc-101341 | 200 µg/ml | $316.00 |