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Hsp70-interacting protein (HspBP1) belongs to a family of eukaryotic proteins identified as nucleotide exchange factors for Hsp70, which exhibit varying degrees of compartment and species specificity. HspBP1 interferes with the CHIP-induced degradation of immature forms of the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates CFTR maturation. HspBP1 binds to Hsp70, inhibits its activity and promotes dissociation of nucleotides from the Hsp70 ATPase domain. It is a protein mainly expressed in heart and skeletal muscle.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps HspBP1 (E-3) | sc-398319 | 200 µg/ml | $316.00 | |||
HspBP1 (E-3): m-IgG Fc BP-HRP Kit | sc-540931 | 200 µg Ab; 10 µg BP | $354.00 | |||
HspBP1 (E-3): m-IgG1 BP-HRP Kit | sc-542472 | 200 µg Ab; 20 µg BP | $354.00 |