ACCÈS RAPIDE AUX LIENS
Pre-mRNA splicing is a critical step in the posttranscriptional regulation of gene expression. Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) is involved in RNA processing and is necessary for efficient pre-mRNA splicing. hnRNP is widely expressed and developmentally regulated. hnRNP Q interacts with survival motor neuron protein (SMN). Loss of function of SMN results in spinal muscular atrophy, a common neurodegenerative disease. The most common deletion in SMN genes disrupts the interaction between SMN and hnRNP Q. hnRNP Q is upregulated after midnight, and this upregulation correlates with an abrupt decline in AANAT, the key enzyme in melatonin synthesis. Rhythmic AANAT mRNA degradation mediated in part by hnRNP Q implicates this enzyme in the regulation of circadian oscillation.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps hnRNP Q (G-6) | sc-271016 | 200 µg/ml | $316.00 | |||
hnRNP Q (G-6): m-IgG Fc BP-HRP Kit | sc-540189 | 200 µg Ab; 10 µg BP | $354.00 | |||
hnRNP Q (G-6): m-IgG2a BP-HRP Kit | sc-546870 | 200 µg Ab; 10 µg BP | $354.00 | |||
Anticorps hnRNP Q (G-6) X | sc-271016 X | 200 µg/0.1 ml | $316.00 |