Anticorps hnRNP A2/B1 (B-8): sc-393726
- L'Anticorps hnRNP A2/B1 (B-8) est un monoclonal de souris IgG3 (chaîne légère kappa) fourni en 200 µg/ml
- spécifique d'un épitope situé entre les acides aminés 226-255 au niveau d'une région interne de hnRNP A2/B1 d'origine human
- recommandé pour la détection de hnRNP A2/B1 d'origine mouse, rat et human par WB, IP, IF et ELISA
- Voir hnRNP A2/B1 (B-7): sc-374053 pour d'autres anticorps conjugués hnRNP A2/B1, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- Le m-IgG3 BP-HRP et le m-IgGκ BP-HRP sont les réactifs de détection secondaire préférés pour l'anticorps hnRNP A2/B1 (B-8) pour les applications WB. Ces réactifs sont désormais proposés en lots avec l'anticorps hnRNP A2/B1 (B-8)(voir les informations relatives à la commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of poly-peptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins are localized to the nucleus; however some shuttle between the nucleus and the cytoplasm. The A/B subfamily of hnRNPs include A1, A2/B1, A3 and A0, and in Xenopus, hnRNP A1, A2 and A3 are ubiquitously expressed throughout development as well as in adult tissues. hnRNP A1 and A2/B1 regulate the processing of pre-mRNA by directly antagonizing the association of various splicing factors and by influencing the splice site selection on pre-mRNA. The hnRNP A0 gene is distinct from the other A/B family members, and it encodes a low-abundance protein, which is implicated in mRNA stability.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps hnRNP A2/B1 (B-8) | sc-393726 | 200 µg/ml | $316.00 | |||
hnRNP A2/B1 (B-8): m-IgGκ BP-HRP Kit | sc-535875 | 200 µg Ab; 40 µg BP | $354.00 | |||
hnRNP A2/B1 (B-8): m-IgG3 BP-HRP Kit | sc-550314 | 200 µg Ab; 40 µg BP | $354.00 | |||
hnRNP A2/B1 (B-8) peptide neutralisant | sc-393726 P | 100 µg/0.5 ml | $68.00 |