Anticorps HNF-1α (2): sc-135939
- L'anticorps HNF-1 alpha 2 est un monoclonal IgG1 de souris, cité dans 6 publications, fourni en 200 µg/ml
- dirigé contre les acides aminés 70-269 de HNF-1α d'origine mouse
- recommandé pour la détection de HNF-1α d'origine mouse, rat et human par WB, IP et IF
- Voir HNF-1α (F-7): sc-393925 pour d'autres anticorps conjugués HNF-1α, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour HNF-1α Antibody (2) for WB applications. Ces réactifs sont désormais proposés en lots avec HNF-1α Antibody (2)(voir les informations de commande ci-dessous).
HNF-1 (α and β), HNF-3 (α, β and γ), HNF-4 (α and γ), and HNF-6 compose, in part, a homoeprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. HNF-3α, HNF-3β and HNF-3γ regulate the transcription of numerous hepatocyte genes in adult liver. HNF-3α and HNF-3β have also been shown to be involved in gastrulation events such as body axis formation. HNF-4α and HNF-4γ have been shown to be important for early embryo development. HNF-4α is expressed in liver, kidney, pancreas, small intestine, testis and colon; and HNF-4γ is expressed in each of these tissues except liver. HNF-6 has been shown to bind to the promoter of HNF-3β, which indicates a potential role of HNF-6 in gut endoderm epithelial cell differentiation. Evidence suggests that HNF-6 may also be a transcriptional activator for at least 22 other hepatocyte-enriched genes, including cytochrome P450 2C13 and α-1 antitrypsin.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps HNF-1α (2) | sc-135939 | 200 µg/ml | $316.00 | |||
HNF-1α (2): m-IgG Fc BP-HRP Kit | sc-539889 | 200 µg Ab; 10 µg BP | $354.00 | |||
HNF-1α (2): m-IgG1 BP-HRP Kit | sc-541766 | 200 µg Ab; 20 µg BP | $354.00 |