Anticorps Helicobacter pylori OMP (6621): sc-58137

Helicobacter pylori is a bacterium that infects the mucus lining of mammalian stomach and duodenum and may cause peptic ulcers, gastritis and duodenitis. It is estimated that about 66% of the world population are infected by the bacterium, though most do not experience symptoms. This spiral-shaped Gram-negative bacterium is unique in that it can thrive in the highly acidic environment of the stomach. Helicobacter pylori can exist in a number of locations: in the mucus; attached to epithelial cells; or inside of vacuoles in epithelial cells, where it produces adhesins that bind to membrane-associated lipids and carbohydrates to help its adhesion to epithelial cells. Helicobacter pylori contains a hydrogenase enzyme and obtains energy by oxidizing molecular hydrogen produced by other intestinal bacteria. It also excretes urease in order to convert urea into ammonia and bicarbonate which neutralizes the acidic environment of the stomach. Helicobacter pylori OMPs (Outer membrane proteins) are involved in Helicobacter pylori adhesion and can cause signal transduction events in host cells.

L'anticorps Helicobacter pylori OMP préféré est l'Anticorps Helicobacter pylori OMP (BDI176): sc-57779.