The condensin complex plays a role in the resolution and segregation of sister chromatids during mitosis and some aspects of mitotic chromosome assembly. Cdc2 phosphorylation of the complex leads to its activation and association with chromosome arms and condensation. Condensin complexes are heteropentamers comprised of two SMC (structural maintenance of chromosomes) subunits and three non-SMC subunits. The SMC family includes SMC1 (also known as SMC1α and SCMB), which associates with SMC3 (also known as hCAP and Bamacan), SMC2 (also known as hCAP-E), which associates with SMC4 (also known as hCAP-C), and SMC5, which associates with SMC6. hCAP-D3 (non-SMC condensin II complex subunit D3), also known as NCAPD3 or KIAA0056, is a 1498 amino acid nuclear protein that contains four HEAT repeats and is a member of the condensin-2 complex.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps hCAP-D3 (283.7) | sc-101016 | 100 µg/ml | $333.00 |