The H2 gene complex encodes for MHC Class I molecules that are histocompatibility antigens consisting of heterodimers of highly polymorphic alpha chains non-covalently associated with the invariant β2 microglobulin cell types. MHC Class I molecules present endogenously synthesised peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. These antigens are expressed on most nucleated cells and levels of expression varies depending on cell type. The expression of MHC Class I antigens on thymic epithelial cells regulates the positive and negative selection of CD8+ T cells during T cell ontogeny. H2-Db is an MHC Class I molecule that may inhibit or activate natural killer (NK) cells.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps H2-Db (5K48) | sc-71198 | 100 µg/ml | $316.00 | |||
Anticorps H2-Db (5K48) FITC | sc-71198 FITC | 100 tests in 2 ml | $330.00 | |||
Anticorps H2-Db (5K48) L | sc-71198 L | 100 µg/0.1 ml | $316.00 | |||
Anticorps H2-Db (5K48) PE | sc-71198 PE | 100 tests in 2 ml | $343.00 |