ACCÈS RAPIDE AUX LIENS
GSTO1 (glutathione S-transferase omega 1), also known as p28 or GSTTLp28, is a 241 amino acid protein that localizes to the cytoplasm and contains both an N-terminal and a C-terminal GST domain. Expressed ubiquitously with highest expression in heart, liver and skeletal muscle, GSTO1 exists as a homodimer that functions as both a glutathione-dependent thiol transferase and a dehydroascorbate reductase. Specifically, GSTO1 catalyzes the reaction of glutathione with a wide variety of organic compounds to form thioethers, a process that is essential for the metabolism and detoxification of a variety of xenobiotics and carcinogens. Human GSTO1 shares 70% sequence homology with its rodent counterpart, suggesting a conserved role between species. Polymorphisms in the gene encoding GSTO1 may be associated with the development of childhood acute lymphoblastic leukemia, Parkinson's disease and Alzheimer disease.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps GSTO1 (6) | sc-130318 | 200 µg/ml | $316.00 | |||
GSTO1 (6): m-IgG Fc BP-HRP Kit | sc-537320 | 200 µg Ab; 10 µg BP | $354.00 | |||
GSTO1 (6): m-IgGκ BP-HRP Kit | sc-534560 | 200 µg Ab; 40 µg BP | $354.00 |