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GRWD1 (glutamate-rich WD repeat-containing protein 1), also known as WDR28 or KIAA1942, is a 446 amino acid protein that contains five WD repeats. Localizing to the nucleus, GRWD1 is a member of the 50S and 80S preribosomal complexes and may play a role in ribosome biogenesis. The gene encoding GRWD1 maps to human chromosome 19q13.33 and mouse chromosome 7 B4. Consisting of around 63 million bases with over 1,400 genes, human chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fcα receptors. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps GRWD1 (B-7) | sc-514125 | 200 µg/ml | $316.00 | |||
GRWD1 (B-7): m-IgGκ BP-HRP Kit | sc-536229 | 200 µg Ab; 40 µg BP | $354.00 | |||
GRWD1 (B-7): m-IgG2b BP-HRP Kit | sc-549526 | 200 µg Ab; 10 µg BP | $354.00 |