Gγ 1 Antibody (1F8): sc-517057
- Gγ 1 Antibody (1F8) is a mouse monoclonal IgG2a κ Gγ 1 antibody provided at 100 µg/ml
- raised against amino acids 1-74 representing full length Gγ 1 of human origin
- recommended for detection of Gγ 1 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Gγ 1 Antibody (1F8). This work is in progress.
Gγ 1 Antibody (1F8) is a mouse monoclonal IgG2a kappa light chain antibody that detects the G gamma 1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-G gamma 1 antibody (1F8) is available as the non-conjugated format. G gamma 1 protein plays a crucial role in the function of heterotrimeric G proteins, which are essential for transmitting signals from cell surface receptors to various intracellular effectors. These proteins are integral to numerous physiological processes, including sensory perception, immune responses, and cellular growth. G gamma 1 subunit, in particular, is involved in the regulation of G protein-coupled receptor signaling pathways, which are pivotal for maintaining cellular homeostasis and responding to external stimuli. Understanding the interactions and regulatory mechanisms of G gamma 1 is vital, as dysregulation of G protein signaling can lead to various diseases, including cancer and cardiovascular disorders. G gamma 1 (1F8) antibody is an invaluable tool for researchers aiming to explore the complexities of G protein signaling and its implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Gγ 1 Antibody (1F8) References:
- Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes. | Hurowitz, EH., et al. 2000. DNA Res. 7: 111-20. PMID: 10819326
- Different beta-subunits determine G-protein interaction with transmembrane receptors. | Kleuss, C., et al. 1992. Nature. 358: 424-6. PMID: 1322501
- Activation of cytosolic phosphoinositide phospholipase C by G-protein beta gamma subunits. | Blank, JL., et al. 1992. J Biol Chem. 267: 23069-75. PMID: 1331076
- Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA. | von Weizsäcker, E., et al. 1992. Biochem Biophys Res Commun. 183: 350-6. PMID: 1543505
- Diversity of G proteins in signal transduction. | Simon, MI., et al. 1991. Science. 252: 802-8. PMID: 1902986
- G protein diversity is increased by associations with a variety of gamma subunits. | Gautam, N., et al. 1990. Proc Natl Acad Sci U S A. 87: 7973-7. PMID: 2122451
- Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human. | Blatt, C., et al. 1988. Proc Natl Acad Sci U S A. 85: 7642-6. PMID: 2902634
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gγ 1 Antibody (1F8) | sc-517057 | 100 µg/ml | $322.00 |