The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1 and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by a variety of agents and function as transcriptional regulators for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers that bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Fra1 (F-8) | sc-271657 | 200 µg/ml | $316.00 | |||
Fra1 (F-8): m-IgG Fc BP-HRP Kit | sc-537675 | 200 µg Ab; 10 µg BP | $354.00 | |||
Fra1 (F-8): m-IgGκ BP-HRP Kit | sc-535016 | 200 µg Ab; 40 µg BP | $354.00 | |||
Fra1 (F-8): m-IgG1 BP-HRP Kit | sc-545299 | 200 µg Ab; 20 µg BP | $354.00 | |||
Fra1 (F-8) peptide neutralisant | sc-271657 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps Fra1 (F-8) X | sc-271657 X | 200 µg/0.1 ml | $316.00 |