Anticorps FOXP3 (6H3C5H3): sc-65988
- L'anticorps FOXP3 6H3C5H3 est un monoclonal IgG2b de souris, cité dans 2 publications, fourni en 200 µg/ml
- soulevée contre le recombinant tronqué purifié FOXP3 d'origine mouse
- recommandé pour la détection de FOXP3 d'origine mouse, rat et human par WB, IP et FCM
- disponible conjugué soit à la phycoérythrine soit à la FITC pour IF, IHC(P) et FCM
- Voir FOXP3 (2A11G9): sc-53876 pour d'autres anticorps conjugués FOXP3, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire FOXP3 (6H3C5H3). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. The gene encoding human FOXP1 maps to chromosome 3p14.1, and the gene encoding human FOXP2 maps to chromosome 7q31. The gene encoding FOXP3, a third member of this family, maps to chromosome Xp11.23. Mutations in this gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein, also known as scurfin, is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps FOXP3 (6H3C5H3) | sc-65988 | 200 µg/ml | $316.00 | |||
Anticorps FOXP3 (6H3C5H3) FITC | sc-65988 FITC | 200 µg/ml | $330.00 | |||
Anticorps FOXP3 (6H3C5H3) PE | sc-65988 PE | 200 µg/ml | $343.00 |