
QUICK LINKS
FMNL1 (2369E4a) is a mouse monoclonal IgG1 antibody. Formin-like protein 1 (FMNL1, formin-related protein, Frl) is a 1,094 amino acid protein encoded by the mouse gene Fmnl1. FMNL1 belongs to the formin homology family and has one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain, and one GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. Formins are a conserved class of proteins expressed in all eukaryotes, with known roles in generating cellular Actin-based structures. FMNL1 plays a role in controlling cell motility and survival of macrophages. FMNL1 interacts with Rac 1, PFN1 and PFN2, blocks apoptotic cell death, and inhibits cell adhesion and migration. FMNL1 is located in the cytoplasm and shows high expression in the spleen, lymph nodes and bone marrow cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FMNL1 Antibody (2369E4a) | sc-81274 | 100 µg/ml | $339.00 | |||
FMNL1 Antibody (2369E4a): m-IgG Fc BP-HRP Bundle | sc-551793 | 100 µg Ab; 10 µg BP | $361.00 |