FLAD1 Antibody (H-7): sc-377286

FLAD1 Antibody (H-7) is a mouse monoclonal IgG2a antibody that detects FLAD1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FLAD1, also known as FAD1 or FADS, is a 587 amino acid protein that plays a crucial role in the metabolic pathway converting riboflavin into flavin adenine dinucleotide (FAD), a vital redox cofactor involved in numerous biological processes, including cellular respiration and energy production. The protein′s N-terminus is part of the moaB/mog family, while its C-terminus belongs to the PAPS reductase family, highlighting diverse functional capabilities. FLAD1 exists in five alternatively spliced isoforms and is primarily localized in the cytoplasm, where FLAD1 utilizes magnesium as a cofactor for enzymatic activity. Notably, FLAD1 is encoded by a gene located on human chromosome 1, which is significant as this chromosome harbors over 3,000 genes and is implicated in various cancers, including head and neck cancer, malignant melanoma, and multiple myeloma, due to the presence of genetic aberrations. The potential non-functionality of the molybdenum cofactor biosynthesis protein-like region of FLAD1 further emphasizes the importance of understanding FLAD1 structure and function in the context of cellular metabolism and disease. Anti-FLAD1 antibody (H-7) is an essential tool for researchers investigating the role of this protein in health and disease.

The preferred FLAD1 antibody is FLAD1 Antibody (G-4): sc-376819.