Filamin 1 Antibody (1.BB.804): sc-58762
- Filamin 1 Antibody (1.BB.804) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against full length platelet Filamin 1 of human origin
- recommended for detection of Filamin 1 from platelets, lymphocytes, fibroblasts and smooth muscle of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See Filamin 1 (E-3): sc-17749 for Filamin 1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Filamin 1 Antibody (1.BB.804) for WB and IHC(P) applications. These reagents are now offered in bundles with Filamin 1 Antibody (1.BB.804) (see ordering information below).
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Filamin 1 (1.BB.804) is a mouse monoclonal IgG1 antibody. Caldesmon, Filamin 1, Nebulin, and Villin are differentially expressed and regulated actin-binding proteins. Both muscular (CDh) and non-muscular (CDl) forms of Caldesmon bind to actin, calmodulin, and myosin. CDh appears predominantly on thin filaments in smooth muscle, while CDl shows wide expression in non-muscle tissues and cells. Filamin 1 exists as a homodimer and functions to crosslink actin to filaments across various tissues. Nebulin, a large filamentous protein specific to muscle tissue, may function as a ruler for filament length, with several isoforms produced through alternative exon usage. Villin, regulated by Ca2+, serves as the major structural component of the brush border in absorptive cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Filamin 1 Antibody (1.BB.804) | sc-58762 | 200 µg/ml | $322.00 | |||
Filamin 1 Antibody (1.BB.804): m-IgG Fc BP-HRP Bundle | sc-539096 | 200 µg Ab; 10 µg BP | $361.00 | |||
Filamin 1 Antibody (1.BB.804): m-IgG1 BP-HRP Bundle | sc-541255 | 200 µg Ab; 20 µg BP | $361.00 |