The exosome is a multisubunit complex of 3' to 5' exoribonucleases. It is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements in their untranslated 3' region. EXOSC8 (exosome component 8), also known as p9, CIP3 (CBP-interacting protein 3), EAP2, OIP2 (Opa-interacting protein 2), RRP43 (Ribosomal RNA-processing protein 43) or Rrp43p, is a component of the exosome multienzyme ribonuclease complex. It belongs to the RNase PH family and localizes to the nucleolus. EXOSC8 is one of the six RNase-PH domain subunits of the exosome. Together, these six subunits form a PNPase-like ring. EXOSC8 is required for the processing of the 7S pre-RNA. In addition to its numerous interactions with other proteins, EXOSC8 can also interact with itself.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps EXOSC8 (2336C2b) | sc-81561 | 100 µg/ml | $333.00 |