

Endoglin Antibody (RM0030-6J9) is a rat monoclonal IgG2a antibody that detects Endoglin in mouse samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Endoglin, also known as CD105, plays a crucial role in angiogenesis and vascular remodeling, making anti-Endoglin antibody (RM0030-6J9) essential for studying normal blood vessel structure and function. Endoglin is primarily located on the surface of vascular endothelial cells, where Endoglin interacts with other members of the transforming growth factor-beta (TGFβ) superfamily, facilitating the binding of ligands such as TGFβ1 and BMPs. Proper functioning of Endoglin is vital, as mutations in Endoglin are linked to hereditary hemorrhagic telangiectasia (HHT), a disorder characterized by abnormal blood vessel formation and increased risk of bleeding. Endoglin′s location in endothelial cells underscores Endoglin′s role in regulating vascular integrity and response to injury, highlighting Endoglin′s importance in both normal physiology and disease states. Endoglin (RM0030-6J9) antibody serves as an invaluable tool for researchers studying vascular biology and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Endoglin/CD105 Antibody (RM0030-6J9) | sc-101443 | 100 µg/ml | $322.00 |