Date published: 2026-5-21

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Endoglin/CD105 Antibody (RM0030-6J9): sc-101443

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Datasheets
  • Endoglin/CD105 Antibody (RM0030-6J9) is a rat monoclonal IgG2a, cited in 3 publications, provided at 100 µg/ml
  • raised against recombinant Endoglin of mouse origin
  • recommended for detection of Endoglin of mouse origin by WB, IP, IF and IHC(P)
  • See Endoglin/CD105 (P3D1): sc-18838 for Endoglin/CD105 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Endoglin/CD105 Antibody (RM0030-6J9). This work is in progress.
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Endoglin Antibody (RM0030-6J9) is a rat monoclonal IgG2a antibody that detects Endoglin in mouse samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Endoglin, also known as CD105, plays a crucial role in angiogenesis and vascular remodeling, making anti-Endoglin antibody (RM0030-6J9) essential for studying normal blood vessel structure and function. Endoglin is primarily located on the surface of vascular endothelial cells, where Endoglin interacts with other members of the transforming growth factor-beta (TGFβ) superfamily, facilitating the binding of ligands such as TGFβ1 and BMPs. Proper functioning of Endoglin is vital, as mutations in Endoglin are linked to hereditary hemorrhagic telangiectasia (HHT), a disorder characterized by abnormal blood vessel formation and increased risk of bleeding. Endoglin′s location in endothelial cells underscores Endoglin′s role in regulating vascular integrity and response to injury, highlighting Endoglin′s importance in both normal physiology and disease states. Endoglin (RM0030-6J9) antibody serves as an invaluable tool for researchers studying vascular biology and related pathologies.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Endoglin/CD105 Antibody (RM0030-6J9)

sc-101443
100 µg/ml
$322.00

Hi, is this the same antibody as the discontinued abcam ab56298 clone number RM0030-6J9? Thanks

Asked by: Kabir
Thank you for your question. Yes, this is the same clone.
Answered by: Technical Support
Date published: 2019-04-13

Can sc-101443: Endoglin (RM0030-6J9) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: TinTin
Thank you for your question. Yes, sc-101443: Endoglin (RM0030-6J9) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 3 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB -SCBT QC
Date published: 2015-06-21
Rated 3 out of 5 by from Published IF data using human U251 cell lysatesPublished IF data using human U251 cell lysates. -SCBT Publication Review
Date published: 2013-11-12
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Endoglin/CD105 Antibody (RM0030-6J9) is rated 3.0 out of 5 by 2.
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