The cytochrome P450 family is responsible for oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. The cytochrome P4502C subfamily comprises a group of constitutive microsomal hemoproteins which are expressed primarily in liver and which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. In humans, this subfamily is responsible for metabolism of a variety of therapeutic drugs such as warfarin, mephenytoin, omeprazole, and anti-inflammatory drugs. CYP2C6 is a form of rat liver microsomal cytochrome P450 that is expressed and inducible by phenobarbital in differentiated Reuber hepatoma cells that express many hepatocyte-specific genes but is not expressed in the lung, kidney, or brain.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps CYP2C6 (213xB12C6) | sc-73484 | 200 µg/ml | $316.00 | |||
CYP2C6 (213xB12C6): m-IgG Fc BP-HRP Kit | sc-539486 | 200 µg Ab; 10 µg BP | $354.00 | |||
CYP2C6 (213xB12C6): m-IgG1 BP-HRP Kit | sc-541516 | 200 µg Ab; 20 µg BP | $354.00 |