Anticorps cyclin A (25): sc-136253
- L'anticorps cyclin A 25 est un monoclonal IgG1 de souris, cité dans 3 publications, fourni en 50 µg/0.5 ml
- dirigé contre les acides aminés 26-144 de cyclin A d'origine human
- recommandé pour la détection de cyclin A d'origine human par WB, IP et IF
- Voir cyclin A (B-8): sc-271682 pour d'autres anticorps conjugués cyclin A, dont AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 et 790.
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire cyclin A (25). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin- dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps cyclin A (25) | sc-136253 | 50 µg/0.5 ml | $316.00 |