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The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription as well as mRNA degradation. Various subunits within the complex are involved in influencing nuclear hormone receptor activities. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome. CNOT11 (CCR4-NOT transcription complex, subunit 11), also known as C40, is a 510 amino acid protein that belongs to the CNOT11 family. CNOT10 and CNOT11 form a subcomplex docked to the CNOT1 scaffold. CNOT11 is encoded by a gene that maps to human chromosome 2q11.2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps CNOT11 (H-7) | sc-390318 | 200 µg/ml | $316.00 | |||
CNOT11 (H-7): m-IgG Fc BP-HRP Kit | sc-540785 | 200 µg Ab; 10 µg BP | $354.00 | |||
CNOT11 (H-7): m-IgG2a BP-HRP Kit | sc-546957 | 200 µg Ab; 10 µg BP | $354.00 | |||
CNOT11 (H-7) peptide neutralisant | sc-390318 P | 100 µg/0.5 ml | $68.00 |