Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
ACCÈS RAPIDE AUX LIENS
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
CDKAL1 Antibody (E-9) is a high quality monoclonal CDKAL1 antibody (also designated CDKAL1 antibody) suitable for the detection of the CDKAL1 protein of mouse, rat and human origin. CDKAL1 Antibody (E-9) is available as both the non-conjugated anti-CDKAL1 antibody form, as well as multiple conjugated forms of anti-CDKAL1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Cell cycle progression is controlled, in part, by a family of cyclin dependent kinases (Cdks) that work to phosphorylate key substrates involved in each phase of cell cycle progression. Cdks are the catalytic subunits of serine/threonine protein kinases, a large family of proteins that act as regulators of the eukaryotic cell cycle. CDKAL1 (Cdk5 regulatory subunit associated protein 1-like 1) is a 579 amino acid single-pass membrane protein that contains one TRAM domain and is similar to Cdk5 regulatory subunit associated proteins (CDK5RAPs). Expressed in pancreas, brain and skeletal muscle, CDKAL1 uses iron as a cofactor and is involved in glucose-stimulated insulin secretion. Defects in the gene encoding CDKAL1 impair insulin secretion and are associated with the development of type 2 diabetes. Multiple isoforms of CDKAL1 exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Do you have a recombinant Cdkal1 protein to use as a standard in ELISA when using the E9 Cdkal 1 primary antibody?
Posée par: Minnie
Thank you for your question. No, we do not have a recombinant CDKAL1 protein that is commercially available.
Répondue par: Technical Support
Date de publication: 2019-08-17
I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with CDKAL1 (E-9): sc-393447 monoclonal antibody?
Posée par: DefinitelyNotMatt
We recommend using one of our our exclusive Mouse IgG Binding Proteins (m-IgGλ) conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here:
Rated 5 de
Very good Western blot data of CDKAL1 expressionVery good Western blot data of CDKAL1 expression in Hep G2, U-2 OS and Jurkat whole cell lysates and human skeletal muscle and human pancreas tissue extracts. -SCBT QC
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