Anticorps Cdc34B (C-4): sc-376427
- L'Anticorps Cdc34B (C-4) est un monoclonal de souris IgG1 (chaîne légère kappa) fourni en 200 µg/ml
- dirigé contre les acides aminés 188-238 situés au niveau C-terminus de Cdc34B d'origine human
- recommandé pour la détection de Cdc34B d'origine mouse, rat et human par WB, IP, IF et ELISA
- m-IgG Fc BP-HRP et 1 BP-HRP">m-IgG1 BP-HRP sont les réactifs de détection secondaire préférés pour Cdc34B Antibody (C-4) for WB applications. Ces réactifs sont désormais proposés en lots avec Cdc34B Antibody (C-4)(voir les informations de commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc34B, also known as UBE2R2 (Ubiquitin-conjugating enzyme E2 R2) or UBC3B, is a 238 amino acid member of the E2 ubiquitin-conjugating enzyme family. Similar to Cdc34, Cdc34B functions to catalytically attach ubiquitin to various proteins, such as β-TrCP (an F-box protein that mediates β-catenin degradation), via an ATP-dependent reaction that yields AMP, a diphosphate and a ubiquitin-tagged protein. Cdc34B can be phosphorylated by the protein kinase CK2 (Casein kinase II), thereby allowing Cdc34B to regulate β-TrCP substrate recognition and, ultimately, enhance β-catenin degradation. Due to its ability to control β-TrCP activity, Cdc34B is thought to play a key role in cell cycle progression.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Cdc34B (C-4) | sc-376427 | 200 µg/ml | $316.00 | |||
Cdc34B (C-4): m-IgG Fc BP-HRP Kit | sc-540568 | 200 µg Ab; 10 µg BP | $354.00 | |||
Cdc34B (C-4): m-IgG1 BP-HRP Kit | sc-542212 | 200 µg Ab; 20 µg BP | $354.00 |