Molecular structure of Carprofen, CAS Number: 53716-49-7
Carprofen (CAS 53716-49-7)
Alternate Names:
Imadyl; Rimadyl; 6-Chloro-a-methyl-9H-carbazole-2-acetic acid
Application:
Carprofen is an antiinflammatory inhibitor of COX-2
CAS Number:
53716-49-7
Purity:
≥98%
Molecular Weight:
273.71
Molecular Formula:
C15H12ClNO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Carprofen is a non-steroidal antiinflammatory compound whose mechanism of action is dependent upon inhibiting the production of COX-2 and other sources of prostaglandins. Prostaglandins are lipid compounds that perform a wide range of biological functions. The study of carprofen and similar compounds can contribute to the broader field of enzymology by highlighting the importance of enzyme inhibitors in regulating biological pathways. In the context of materials science, the mechanisms by which carprofen interacts with biological molecules can inspire the design of biomimetic materials and coatings that modulate specific biochemical pathways.
Carprofen (CAS 53716-49-7) References
- Carprofen neither reduces postoperative facial expression scores in rabbits treated with buprenorphine nor alters long term bone formation after maxillary sinus grafting. | Hedenqvist, P., et al. 2016. Res Vet Sci. 107: 123-131. PMID: 27473985
- Clinical evaluation of postoperative analgesia, cardiorespiratory parameters and changes in liver and renal function tests of paracetamol compared to meloxicam and carprofen in dogs undergoing ovariohysterectomy. | Hernández-Avalos, I., et al. 2020. PLoS One. 15: e0223697. PMID: 32059002
- Carprofen elicits pleiotropic mechanisms of bactericidal action with the potential to reverse antimicrobial drug resistance in tuberculosis. | Maitra, A., et al. 2020. J Antimicrob Chemother. 75: 3194-3201. PMID: 32790867
- Pharmacokinetics of carprofen and firocoxib for medication control in racing greyhounds. | Morris, TH., et al. 2020. Aust Vet J. 98: 578-585. PMID: 32875570
- The effect of combined carprofen and omeprazole administration on gastrointestinal permeability and inflammation in dogs. | Jones, SM., et al. 2020. J Vet Intern Med. 34: 1886-1893. PMID: 32893926
- Pharmacokinetics of carprofen in anaesthetized pigs: a preliminary study. | Bošnjak, M., et al. 2021. Vet Anaesth Analg. 48: 35-41. PMID: 33303396
- Strength and Sterility of Stock and Diluted Carprofen Over Time. | Xu, JJ., et al. 2021. J Am Assoc Lab Anim Sci. 60: 470-474. PMID: 33972008
- Pharmacokinetics and Bioavailability of Carprofen in Rainbow Trout (Oncorhynchus mykiss) Broodstock. | Uney, K., et al. 2021. Pharmaceutics. 13: PMID: 34208822
- Toxic Effects of High-dose Meloxicam and Carprofen on Female CD1 Mice. | Kendall, LV., et al. 2022. J Am Assoc Lab Anim Sci. 61: 75-80. PMID: 34920791
- Concentration of carprofen in the milk of lactating bitches after cesarean section and during inflammatory conditions. | Ferrari, D., et al. 2022. Theriogenology. 181: 59-68. PMID: 35063922
- Grapiprant or carprofen following ovariohysterectomy in the cat: analgesic efficacy, hematological, biochemical and urinalysis evaluation. | Teixeira, LG., et al. 2022. J Feline Med Surg. 24: e153-e162. PMID: 35531962
- Pharmacokinetics of carprofen following single and repeated intravenous administrations of different doses in sheep. | Corum, O., et al. 2022. J Vet Pharmacol Ther. 45: 481-487. PMID: 35748159
- Pharmacokinetics and bioavailability of carprofen in sheep. | Coskun, D., et al. 2022. J Vet Pharmacol Ther. 45: 543-549. PMID: 35768899
- Scanning electron microscopy of the prostomium and anterior segments of the earthworm (Lumbricus terrestris L., Eisenia foetida Sav.). | Aros, B., et al. 1978. Z Mikrosk Anat Forsch. 92: 753-69. PMID: 749397
- The interaction of arginine 106 of human prostaglandin G/H synthase-2 with inhibitors is not a universal component of inhibition mediated by nonsteroidal anti-inflammatory drugs. | Greig, GM., et al. 1997. Mol Pharmacol. 52: 829-38. PMID: 9351974
Inhibitor of:
Cox-2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Carprofen, 1 g | sc-205621 | 1 g | $82.00 | |||
Carprofen, 5 g | sc-205621A | 5 g | $368.00 |