ACCÈS RAPIDE AUX LIENS
Pro-apototic Bcl-2 family members promote cell death by neutralizing their anti-apoptotic relatives, which otherwise maintain cell viability by regulating caspase activity. Bim belongs to the BH3-only subgroup of Bcl-2 related proteins, and exists in three distinct isoforms, BimS (short), BimL (long) and BimEL (extra long). ERK1/2 phosphorylates BimEL, resulting in rapid degradation of the isoform via the proteasome pathway. At least three sites for ERK1/2 phosphorylation exist on BimEL, whereas ERK1/2 does not effect BimS and BimL, implying a unique role for BimEL in cell survival signaling.
Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Bim (Ham 151-149) | sc-130511 | 200 µg/ml | $316.00 | |||
Anticorps Bim (Ham 151-149) FITC | sc-130511 FITC | 200 µg/ml | $330.00 | |||
Anticorps Bim (Ham 151-149) PE | sc-130511 PE | 200 µg/ml | $343.00 |