BAT2 Antibody (A-10): sc-373747
- BAT2 Antibody (A-10) is a mouse monoclonal IgG1 κ BAT2 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 575-609 within an internal region of BAT2 of human origin
- BAT2 Antibody (A-10) is recommended for detection of BAT2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
- TransCruz reagent for ChIP application (sc-373747 X, 200 µg/0.1 ml)
- Anti-BAT2 Antibody (A-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for BAT2 Antibody (A-10) for WB applications. These reagents are now offered in bundles with BAT2 Antibody (A-10) (see ordering information below).
BAT2 Antibody (A-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects BAT2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BAT2 Antibody (A-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. BAT2, also known as G2, is a 2,157 amino acid protein localized in both nucleus and cytoplasm, crucial for regulating pre-mRNA splicing. This localization allows BAT2 to interact with spliceosomal components and other regulatory proteins, influencing gene expression and cellular function. BAT2 gene is situated within a cluster of BAT genes on human chromosome 6, a region significant for involvement in immune response regulation and association with various diseases, including rheumatoid arthritis and insulin-dependent diabetes mellitus. Chromosome 6, spanning 170 million base pairs and constituting nearly 6% of human genome, is linked to several health conditions, such as Porphyria cutanea tarda and Parkinson′s disease, highlighting BAT2′s importance in both normal cellular processes and disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
BAT2 Antibody (A-10) References:
- Genetic contribution of the BAT2 gene microsatellite polymorphism to the age-at-onset of insulin-dependent diabetes mellitus. | Hashimoto, M., et al. 1999. Hum Genet. 105: 197-9. PMID: 10987645
- Association of the major histocompatibility complex with response to infliximab therapy in rheumatoid arthritis patients. | Martinez, A., et al. 2004. Arthritis Rheum. 50: 1077-82. PMID: 15077289
- Antibodies generated by a novel DNA vaccination identify the MHC class III encoded BAT2 polypeptide. | Schneiders, A., et al. 2005. Vaccine. 23: 2540-50. PMID: 15752841
- Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis. | Harney, SM., et al. 2008. Rheumatology (Oxford). 47: 1761-7. PMID: 18835879
- Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach. | McKinnon, E., et al. 2009. Diabetes Obes Metab. 11 Suppl 1: 92-100. PMID: 19143821
- A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain. | Banerji, J., et al. 1990. Proc Natl Acad Sci U S A. 87: 2374-8. PMID: 2156268
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BAT2 Antibody (A-10) | sc-373747 | 200 µg/ml | $322.00 | |||
BAT2 Antibody (A-10): m-IgGκ BP-HRP Bundle | sc-522481 | 200 µg Ab, 40 µg BP | $361.00 | |||
BAT2 Antibody (A-10): m-IgG1 BP-HRP Bundle | sc-533524 | 200 µg Ab; 20 µg BP | $361.00 | |||
BAT2 Antibody (A-10) X | sc-373747 X | 200 µg/0.1 ml | $322.00 | |||
BAT2 Antibody (A-10) AC | sc-373747 AC | 500 µg/ml, 25% agarose | $424.00 | |||
BAT2 Antibody (A-10) HRP | sc-373747 HRP | 200 µg/ml | $322.00 | |||
BAT2 Antibody (A-10) FITC | sc-373747 FITC | 200 µg/ml | $336.00 | |||
BAT2 Antibody (A-10) PE | sc-373747 PE | 200 µg/ml | $349.00 | |||
BAT2 Antibody (A-10) Alexa Fluor® 488 | sc-373747 AF488 | 200 µg/ml | $364.00 | |||
BAT2 Antibody (A-10) Alexa Fluor® 546 | sc-373747 AF546 | 200 µg/ml | $364.00 | |||
BAT2 Antibody (A-10) Alexa Fluor® 594 | sc-373747 AF594 | 200 µg/ml | $364.00 | |||
BAT2 Antibody (A-10) Alexa Fluor® 647 | sc-373747 AF647 | 200 µg/ml | $364.00 | |||
BAT2 Antibody (A-10) Alexa Fluor® 680 | sc-373747 AF680 | 200 µg/ml | $364.00 | |||
BAT2 Antibody (A-10) Alexa Fluor® 790 | sc-373747 AF790 | 200 µg/ml | $364.00 | |||
BAT2 (A-10) Neutralizing Peptide | sc-373747 P | 100 µg/0.5 ml | $69.00 |