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B23 Antibody (7H10B9) is a mouse monoclonal IgG1 antibody that detects B23 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. B23, also known as nucleophosmin, plays a crucial role in ribosomal assembly and the transport of ribosomal RNA, making B23 essential for protein synthesis and cellular function. B23 is predominantly located in the nucleolus, where B23 is involved in the maturation of ribosomal subunits, and proper localization is vital for maintaining efficient ribosome biogenesis. Additionally, B23 undergoes significant post-translational modifications, particularly phosphorylation by Cdc2 kinase during mitosis, which can influence B23′s activity and interactions with other cellular proteins. Anti-B23 antibody (7H10B9) serves as an invaluable tool for researchers studying ribosome assembly, cell cycle regulation, and nucleolar function, providing insights into the molecular mechanisms underlying cellular growth and proliferation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
B23/Nucleophosmin Antibody (7H10B9) | sc-65943 | 100 µg/ml | $322.00 |