Date published: 2026-6-5

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AM 404-d4 (CAS 1185244-71-6)

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Alternate Names:
(5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl-d4)-5,8,11,14-eicosatetraenamide
Application:
AM 404-d4 is a labeled metabolite of the analgesic, Paracetamol
CAS Number:
1185244-71-6
Molecular Weight:
399.60
Molecular Formula:
C26H33D4NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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AM 404-d4, catalogued under the CAS number 1185244-71-6, is a deuterated derivative of AM 404, a compound known for its role in modulating various biochemical pathways. The addition of four deuterium atoms to AM 404 enhances its stability and reduces the rate of metabolic degradation, making AM 404-d4 particularly valuable in research applications where isotopic labeling is crucial. This chemical is extensively used in mass spectrometry-based studies to differentiate and quantify the parent compound AM 404 from its metabolites during metabolic profiling experiments. The deuterium atoms present in AM 404-d4 serve as stable isotopic labels that do not alter the chemical properties of the compound significantly but provide distinct mass spectral properties. This characteristic allows researchers to trace the metabolic fate of AM 404 in complex biological systems with greater accuracy and sensitivity. Additionally, due to its stable labeled nature, AM 404-d4 is instrumental in pharmacokinetic studies, enabling the examination of the dynamics of absorption, distribution, metabolism, and excretion of AM 404 without the interference from similarly structured compounds. Its use in non-medical research applications provides deeper understanding of biochemical pathways in experimental and analytical chemistry settings, focusing on the detailed study of molecular interactions and transformations.


AM 404-d4 (CAS 1185244-71-6) References

  1. Metabolism of AM404 From Acetaminophen at Human Therapeutic Dosages in the Rat Brain.  |  Muramatsu, S., et al. 2016. Anesth Pain Med. 6: e32873. PMID: 27110534

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

AM 404-d4, 1 mg

sc-217618
1 mg
$561.00