alpha Tubulin Antibody (10D8): sc-53646

α Tubulin Antibody (10D8) is a mouse monoclonal IgM antibody that detects α Tubulin across a broad range of species, and is recommended for use in applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). α Tubulin monoclonal antibody (10D8) is raised against full-length α Tubulin derived from human sources and provides a valuable tool for studying the microtubule network. α Tubulin is a major structural protein of the cytoskeleton, forming heterodimers with β Tubulin to assemble into microtubules, which are essential for numerous cellular processes, including intracellular transport, cell division, and maintaining cell shape. These microtubules are highly dynamic structures that also play a critical role in the formation of the mitotic spindle during cell division, the organization of organelles, and the movement of cilia and flagella. α Tubulin is primarily located in the cytoplasm, particularly in microtubule networks that extend from the centrosome, a key region for microtubule nucleation. α Tubulin is also present in the axonemes of cilia and flagella, where α Tubulin is essential for their motility and function. α Tubulin undergoes several post-translational modifications, including tyrosination and detyrosination, which are involved in regulating microtubule dynamics and interactions with motor proteins like kinesins and dyneins. These modifications are critical for microtubule stability and are involved in signaling pathways that govern cellular processes such as mitosis, cell migration, and neuronal function. α Tubulin (10D8) antibody is an essential tool for researchers studying microtubule assembly, cellular structure, and protein dynamics across various species.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-alpha Tubulin Antibody (10D8) has 168 citations in a variety of scientific publications.

Primary antibodies like Anti-alpha Tubulin Antibody (10D8) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

alpha Tubulin Antibody (10D8) Specifications

Alternate Product Name: α Tubulin

Product Clone Name: 10D8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids:

Epitope Target: α Tubulin

Epitope Species: human

Product Reactivity/Detection: α Tubulin

Species Reactivity/Detection: broad species

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 168 citations in various scientific publications

Available Conjugates/Forms for alpha Tubulin Antibody (10D8): N/A

The preferred alpha Tubulin antibody is alpha Tubulin Antibody (TU-02): sc-8035.