Date published: 2025-9-7

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Anticorps AKAP 8L (B-6): sc-376338

5.0(3)
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Fiches techniques
  • AKAP 8L anticorps (B-6) est un monoclonal de souris IgG1 (chaîne légère lambda) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 617-647 au niveau C-terminus de AKAP 8L d'origine human
  • recommandé pour la détection de AKAP 8L d'origine mouse, rat et human par WB, IP, IF, IHC(P) et ELISA
  • Le m-IgGλ BP-HRP (protéine de liaison IgGλ de souris-HRP) est le réactif de détection secondaire préféré pour l'anticorps AKAP 8L (B-6) pour les applications WB et IHC(P). Ce réactif est désormais proposé en association avec l'anticorps AKAP 8L (B-6)(voir les informations relatives à la commande ci-dessous). Pour d'autres conjugués m-IgGλ BP, voir notre liste complète de protéines de liaison IgG de souris.

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. The family of RII-anchoring proteins has been designated A-kinase anchoring proteins (AKAP). AKAP 8, also known as AKAP 95, is a nuclear matrix protein predominantly expressed in liver, heart, pancreas, kidney and skeletal muscle. During mitosis, AKAP 8 is recruited to the chromosomes and plays an essential role in mitotic progression. AKAP 8L (AKAP 8-like), also known as HA95 (homologous to AKAP 95 protein), HAP95 (Helicase A-binding protein 95), NAKAP or NAKAP95 (neighbor of AKAP 95), is also a nuclear matrix protein and shares 61% homology and 30% identity with AKAP 8. In addition, AKAP 8L forms a complex with AKAP 8 and HDAC3 and is required for the deacetylation of Histone H3 in mitosis.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps AKAP 8L (B-6)

    sc-376338
    200 µg/ml
    $316.00

    AKAP 8L (B-6): m-IgGλ BP-HRP Kit

    sc-522921
    200 µg Ab, 40 µg BP
    $354.00

    AKAP 8L (B-6) peptide neutralisant

    sc-376338 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-376338 P appropriate for?

    Posée par: Dr Ninau Qelp
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-03-01
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    Rated 5 de 5 de par Band present at expected molecular weightBand present at expected molecular weight in Jurkat whole cell lysate via western blot analysis. -SCBT QC
    Date de publication: 2015-06-21
    Rated 5 de 5 de par WB: positive band in HeLa whole cell lysateWB: positive band in HeLa whole cell lysate. -SCBT QC
    Date de publication: 2015-01-27
    Rated 5 de 5 de par Excellent immunoperoxidase nuclear stainingExcellent immunoperoxidase nuclear staining in formalin fixed, paraffin-embedded human spleen tissue. -SCBT QC
    Date de publication: 2015-01-10
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    Anticorps AKAP 8L (B-6) est évalué 5.0 de 5 de 3.
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