Date published: 2025-9-11

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Anticorps AF-6 (G-7): sc-398370

5.0(1)
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Fiches techniques
  • L'Anticorps AF-6 (G-7) est un monoclonal de souris mouse IgM κ (chaîne légère kappa) fourni en 200 µg/ml
  • spécifique d'un épitope situé entre les acides aminés 1565-1592 près de C-terminus de AF-6 d'origine human
  • recommandé pour la détection de AF-6 d'origine mouse, rat et human par WB, IP, IF et ELISA
  • Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire AF-6 (G-7). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    The dynamics of a cell-cell interface such as tight junctions or adherens junctions are important in many developmental, physiological, and pathological processes. AF-6 (MLLT4: myeloid/lymphoid or mixed-lineage leukemia trans-located to 4) is a 1,612 amino acid protein that contains two N-terminal Ras binding domains (RBD) and a GLGF motif, and is implicated in Ras-mediated signaling events occurring at peripheral cell-cell junctions. AF-6 interacts with F-actin and Profilin in cell-cell junctions, and may modulate Actin modeling near adhesion complexes. Furthermore, AF-6 coordinates junction adhesion molecule (JAM) recruitment to intercellular junctions through a PDZ domain. Developing mice deficient in AF-6 activity display a loss of neuroepithelial polarity, suggesting that AF-6 activity is an important regulator of cell-cell junctions that influence apical/basolateral asymmetry.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps AF-6 (G-7)

    sc-398370
    200 µg/ml
    $316.00

    AF-6 (G-7) peptide neutralisant

    sc-398370 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-398370 P appropriate for?

    Posée par: Professor Griffin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Répondue par: Technical Support
    Date de publication: 2017-02-25
    • y_2025, m_9, d_10, h_9CST
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    Rated 5 de 5 de par Nice Western blot data of AFNice Western blot data of AF-6 expression in non-transfected 293 mouse AF-6 transfected 293 SK-N-MC, Hep G2, PC-12 and NIH/3T3 whole cell lysates. -SCBT QC
    Date de publication: 2013-04-06
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    Anticorps AF-6 (G-7) est évalué 5.0 de 5 de 1.
    • y_2025, m_9, d_10, h_9
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