Date published: 2025-9-7

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Anticorps ADH8 (B-10): sc-390552

5.0(2)
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Fiches techniques
  • L'Anticorps ADH8 (B-10) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
  • dirigé contre les acides aminés 20-259 situés près de la région N-terminus de ADH8 d'origine human
  • recommandé pour la détection de ADH8 d'origine human par WB, IP, IF, IHC(P) et ELISA
  • m-IgG Fc BP-HRP et m-IgG2a BP-HRP sont les réactifs secondaires recommandés pour la détection de l'anticorps ADH8 (B-10) pour des applications de WB and IHC(P). Ces réactifs sont maintenant proposés en kit avec l'anticorps ADH8 (B-10) (voir Informations pour la commande ci-dessous).

    ACCÈS RAPIDE AUX LIENS

    VOIR ÉGALEMENT...

    The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH8, also known as ADHFE1 (alcohol dehydrogenase, iron containing, 1) or HOT, is a 467 amino acid protein that belongs to the iron-containing alcohol dehydrogenase family and localizes to the mitochondrion. Expressed specifically in adult liver, ADH8 functions to catalyze the cofactor-independent oxidation of gamma-hydroxybutyrate to succinic semialdehyde, a reaction that is coupled to the reduction of 2-ketoglutarate to D-2-hydroxyglutarate and occurs at an optimal pH of 7.5. Succinic semialdehyde can then be converted to succinic acid which is used for energy production in the Krebs cycle. Four isoforms of ADH8 exist due to alternative splicing events.

    Pour la Recherche Uniquement. Non destiné à un usage diagnostique ou thérapeutique.

    Informations pour la commande

    Nom du produitRef. CatalogueCOND.Prix HTQTÉFavoris

    Anticorps ADH8 (B-10)

    sc-390552
    200 µg/ml
    $316.00

    ADH8 (B-10): m-IgG Fc BP-HRP Kit

    sc-540816
    200 µg Ab; 10 µg BP
    $354.00

    ADH8 (B-10): m-IgG2a BP-HRP Kit

    sc-546962
    200 µg Ab; 10 µg BP
    $354.00

    Can ADH8 (B-10): sc-390552 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Posée par: Germaine
    Thank you for your question. Yes, ADH8 (B-10): sc-390552 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Répondue par: Technical Support
    Date de publication: 2017-02-27
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    Rated 5 de 5 de par Produced superb immunoperoxidase cytoplasmicProduced superb immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human liver tissue. -SCBT QC
    Date de publication: 2015-04-03
    Rated 5 de 5 de par Satisfactory Western Blot data of ADH8 expressionSatisfactory Western Blot data of ADH8 expression in human liver tissue extract. -SCBT QC
    Date de publication: 2013-03-13
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    Anticorps ADH8 (B-10) est évalué 5.0 de 5 de 2.
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