Date published: 2026-5-25

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3-(4-Hydroxyphenyl)-2(1H)-pyrazinone (CAS 126247-63-0)

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Alternate Names:
USP Amoxicillin Related Compound F; Amoxicillin EP Impurity F
Application:
3-(4-Hydroxyphenyl)-2(1H)-pyrazinone is a potential penicillin impurity
CAS Number:
126247-63-0
Molecular Weight:
188.18
Molecular Formula:
C10H8N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-(4-Hydroxyphenyl)-2(1H)-pyrazinone is a chemical compound that features both a pyrazinone ring and a phenolic group, which contribute to its distinctive biochemical properties. The pyrazinone ring is a versatile heterocyclic structure known for its involvement in various biological interactions, primarily through its ability to bind with biomolecules. The attached hydroxyphenyl group enhances its biochemical activity, particularly its potential to participate in hydrogen bonding and pi-pi interactions, which are crucial in molecular recognition processes. In scientific research, this compound has been utilized to study molecular interactions that depend on these structural features. Its ability to form specific interactions with proteins and other biological macromolecules makes it a useful probe in exploring binding dynamics and enzyme inhibition mechanisms. This is particularly valuable in studies aiming to understand how small molecules can influence and modulate biological pathways through direct interaction with key molecular components. Moreover, 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone serves as a core structure in synthetic chemistry for the development of more complex molecules designed to study or manipulate specific biological functions. Its role in research extends to material science and organic chemistry, where its properties are harnessed to create novel materials with specific electronic or optical characteristics, thus contributing to the advancement of these fields.


3-(4-Hydroxyphenyl)-2(1H)-pyrazinone (CAS 126247-63-0) References

  1. Mechanistic and ecotoxicological studies of amoxicillin removal through anaerobic degradation systems.  |  Busto, RV., et al. 2020. Ecotoxicol Environ Saf. 192: 110207. PMID: 32032860
  2. Ecotoxicology Evaluation of a Fenton-Type Process Catalyzed with Lamellar Structures Impregnated with Fe or Cu for the Removal of Amoxicillin and Glyphosate.  |  Lugo, L., et al. 2023. Int J Environ Res Public Health. 20: PMID: 38131723

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-(4-Hydroxyphenyl)-2(1H)-pyrazinone, 10 mg

sc-470752
10 mg
$572.00