Anticorps 26S Proteasome p48A (12A1): sc-65756
- L'Anticorps 26S Proteasome p48A (12A1) est un monoclonal de souris IgG2a (chaîne légère kappa) fourni en 200 µg/ml
- élevé contre le protéasome 26S purifié à partir d'embryons d'origine Drosophila melanogaster.
- recommandé pour la détection de p48A subunit of the 19S regulatory base complex of the 26S Proteasome d'origine d par WB et IP
- 2a BP-HRP">m-IgG2a BP-HRP est le réactif de détection secondaire préféré pour l'anticorps 26S Proteasome p48A (12A1) pour les applications WB. Ce réactif est désormais proposé en association avec l'anticorps 26S Proteasome p48A (12A1)(voir les informations relatives à la commande ci-dessous).
ACCÈS RAPIDE AUX LIENS
The 26S proteasome is a large complex involved in the intracellular degradation of proteins in eukaryotes. Ubiquitination by E3 ubiquitin ligases targets proteins for degradation by this complex. The 26S proteasome plays an important role in the regulation of many biological processes. It is composed of over 30 different subunits and contains at least two copies of each subunit. Assembly of this large complex is ATP-dependent. Due to its size, it is fairly unstable and often disassociates into subcomplexes (including a 20S core and two 19S regulatory complexes). The 26S proteasome p48A (also known as Rpt3 in yeast and S6 in human) is one of the six ATPase base subunits of the 19S regulatory complex. The 19S regulatory complex recognizes ubiquitinated proteins, removes the ubiquitin chains and translocates the proteins to the 20S core for degradation. The base subunits are involved in protein-chaperone activity. The 26S proteasome p48A is required for the recruitment of the p30 (Rpn12/S14) subunit of the 19S lid.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps 26S Proteasome p48A (12A1) | sc-65756 | 200 µg/ml | $316.00 | |||
26S Proteasome p48A (12A1): m-IgG2a BP-HRP Kit | sc-546001 | 200 µg Ab; 10 µg BP | $354.00 |