Date published: 2026-7-29

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2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (CAS 14812-59-0)

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Alternate Names:
Phosphorochloridous acid cyclic tetramethylethylene ester
Application:
2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane is phosphitylator of alcohols and heteroatomic nucleophiles
CAS Number:
14812-59-0
Molecular Weight:
182.59
Molecular Formula:
C6H12ClO2P
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (CDMP) is used for the phosphitylation of alcohols and heteroatomic nucleophiles, resulting in the formation of useful glycosyl donors and ligands. It is also used in a variety of scientific research applications, including the synthesis of organic compounds and study of enzyme kinetics, protein-protein interactions, and the structure and function of proteins and nucleic acids. 2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane acts as a catalyst in many biochemical reactions, can inhibit the activity of certain enzymes, and has an effect on the expression of certain genes.


2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (CAS 14812-59-0) References

  1. Rapid quantitative analytical tool for characterizing the preparation of biodiesel.  |  Nagy, M., et al. 2010. J Phys Chem A. 114: 3883-7. PMID: 20235605
  2. Oxidation of isoeugenol by salen complexes with bulky substituents.  |  Salanti, A., et al. 2010. Int J Mol Sci. 11: 912-26. PMID: 20479991
  3. A high-resolution phosphorus-31 nuclear magnetic resonance (NMR) spectroscopic method for the non-phosphorus markers of chemical warfare agents.  |  Mazumder, A., et al. 2012. Anal Bioanal Chem. 402: 1643-52. PMID: 22160203
  4. Simultaneous determination of phenolic compounds and triterpenic acids in oregano growing wild in Greece by 31P NMR spectroscopy.  |  Agiomyrgianaki, A. and Dais, P. 2012. Magn Reson Chem. 50: 739-48. PMID: 23001915

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane, 1 g

sc-225283
1 g
$421.00

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane, 5 g

sc-225283A
5 g
$1500.00

2-Chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane, 10 g

sc-225283B
10 g
$2500.00