Date published: 2026-8-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

1,1′-Bis(di-tert-butylphosphino)ferrocene (CAS 84680-95-5)

0.0(0)
Write a reviewAsk a question

CAS Number:
84680-95-5
Molecular Weight:
474.42
Molecular Formula:
C26H44FeP2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

1,1′-Bis(di-tert-butylphosphino)ferrocene, a synthetic molecule, is composed of 26 carbons, 44 hydrogens, one iron atom, and two phosphorus atoms. Its potential applications in scientific research have been extensively studied in recent years. This versatile molecule has found use in a variety of experiments, spanning organic and inorganic chemistry as well as biochemistry. Within the realm of organic chemistry, 1,1′-Bis(di-tert-butylphosphino)ferrocene serves as a ligand, forming coordination compounds that aid in various reactions. In the field of biochemistry, it acts as a catalyst for synthesizing biochemical molecules, including proteins and enzymes. One of the striking features of 1,1′-Bis(di-tert-butylphosphino)ferrocene is its unique mechanism of action. The iron atom in the molecule has the capability to bind with diverse molecules, including proteins and enzymes, forming stable complexes. This binding property allows 1,1′-Bis(di-tert-butylphosphino)ferrocene to function as a catalyst, facilitating the synthesis of vital biochemical molecules. Moreover, the phosphonium salt in the molecule enables interactions with cell membranes, further enhancing its ability to deliver drugs with precision to targeted locations.


1,1′-Bis(di-tert-butylphosphino)ferrocene (CAS 84680-95-5) References

  1. Air stable, sterically hindered ferrocenyl dialkylphosphines for palladium-catalyzed C[bond]C, C[bond]N, and C[bond]O bond-forming cross-couplings.  |  Kataoka, N., et al. 2002. J Org Chem. 67: 5553-66. PMID: 12153253
  2. New ligands for a general palladium-catalyzed amination of aryl and heteroaryl chlorides.  |  Rataboul, F., et al. 2004. Chemistry. 10: 2983-90. PMID: 15214081
  3. A general palladium-catalyzed coupling of aryl bromides/triflates and thiols.  |  Itoh, T. and Mase, T. 2004. Org Lett. 6: 4587-90. PMID: 15548082
  4. Evolution of a fourth generation catalyst for the amination and thioetherification of aryl halides.  |  Hartwig, JF. 2008. Acc Chem Res. 41: 1534-44. PMID: 18681463
  5. Domino carbopalladation-carbonylation: generating quaternary stereocenters while controlling beta-hydride elimination.  |  Seashore-Ludlow, B. and Somfai, P. 2010. Org Lett. 12: 3732-5. PMID: 20687573
  6. Synthesis and X-ray structure determination of highly active Pd(II), Pd(I), and Pd(0) complexes of di(tert-butyl)neopentylphosphine (DTBNpP) in the arylation of amines and ketones.  |  Hill, LL., et al. 2010. J Org Chem. 75: 6477-88. PMID: 20806983
  7. A thiocyanato-bridged copper(I) cubane complex and its application in palladium-catalyzed Sonogashira coupling of aryl halides.  |  Trivedi, M., et al. 2013. Dalton Trans. 42: 12849-52. PMID: 23903662
  8. β-Type glycosidic bond formation by palladium-catalyzed decarboxylative allylation.  |  Xiang, S., et al. 2013. Chemistry. 19: 14047-51. PMID: 24108596
  9. Syntheses, characterization, and structural studies of copper(I) complexes containing 1,1'-bis(di-tert-butylphosphino)ferrocene (dtbpf) and their application in palladium-catalyzed Sonogashira coupling of aryl halides.  |  Trivedi, M., et al. 2014. Dalton Trans. 43: 13620-9. PMID: 25099773
  10. Synthesis of 1,1-Diborylalkenes through a Brønsted Base Catalyzed Reaction between Terminal Alkynes and Bis(pinacolato)diboron.  |  Morinaga, A., et al. 2015. Angew Chem Int Ed Engl. 54: 15859-62. PMID: 26564784
  11. 1,1'-Bis(di-tert-butylphosphino)ferrocene copper(I) complex catalyzed C-H activation and carboxylation of terminal alkynes.  |  Trivedi, M., et al. 2015. Dalton Trans. 44: 20874-82. PMID: 26568456
  12. Iron-Catalyzed Cleavage Reaction of Keto Acids with Aliphatic Aldehydes for the Synthesis of Ketones and Ketone Esters.  |  Zhou, F., et al. 2020. Chemistry. 26: 4246-4250. PMID: 32012367
  13. A highly active copper catalyst for the hydrogenation of carbon dioxide to formate under ambient conditions.  |  Chaudhary, K., et al. 2020. Dalton Trans. 49: 2994-3000. PMID: 32083266

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,1′-Bis(di-tert-butylphosphino)ferrocene, 250 mg

sc-224876
250 mg
$31.00