Date published: 2025-11-24

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Inhibiteurs ZNF391

Zinc finger protein 391" (ZNF391) is a member of the zinc finger protein family, which is characterized by the presence of zinc finger domains-a type of protein structural motif that coordinates zinc ions to stabilize its fold. These motifs are often involved in interactions with DNA, RNA, or other proteins, and they are crucial for a variety of cellular functions, including gene expression, DNA recognition, transcriptional regulation, and signal transduction.ZNF391, like other zinc finger proteins, is presumed to function as a transcription factor, binding to specific DNA sequences to regulate the expression of target genes. The specific DNA-binding activity of ZNF391 is facilitated by its finger-like projections, which enable it to make contact with the major grooves of DNA, influencing the transcriptional machinery of the cell. By acting as a transcriptional regulator, ZNF391 can modulate various biological processes such as cell growth, differentiation, and apoptosis.

The exact physiological role and the spectrum of target genes of ZNF391 are not fully elucidated and remain an area of ongoing research. However, the importance of zinc finger proteins in development and disease processes is well-documented, suggesting that ZNF391 likely plays a significant, albeit currently unclear, role in cellular homeostasis and organismal development.The study of ZNF391 and related zinc finger proteins continues to be a significant focus within molecular biology due to their potential implications in understanding genetic regulation and their potential involvement in various pathologies, including cancer and genetic disorders. By deciphering the specific mechanisms by which ZNF391 influences gene expression, researchers hope to contribute to the broader knowledge of gene regulatory networks and their impact on health and disease.

VOIR ÉGALEMENT...

Nom du produitCAS #Ref. CatalogueQuantitéPrix HTCITATIONS Classement

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

L'actinomycine D inhibe la synthèse de l'ARN, ce qui pourrait avoir un impact sur l'expression de ZNF391 au niveau transcriptionnel.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

Le triptolide inhibe l'ARN polymérase et le NF-κB, affectant potentiellement la transcription de ZNF391 et ses voies de régulation.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$254.00
41
(3)

Le flavopiridol inhibe les kinases cycline-dépendantes, affectant potentiellement la régulation transcriptionnelle de ZNF391 et ses voies associées.

Triamcinolone acetonide

76-25-5sc-205872
sc-205872A
50 mg
250 mg
$56.00
$149.00
(0)

L'acétonide de triamcinolone est un agoniste des récepteurs des glucocorticoïdes, et sa modulation de l'activité transcriptionnelle peut avoir un impact sur l'expression de ZNF391.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

L'α-Amanitine inhibe l'ARN polymérase II, ce qui peut avoir un impact sur la transcription de ZNF391 et de ses cibles en aval.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

La trichostatine A est un inhibiteur d'histone-désacétylase, qui pourrait avoir un impact sur la régulation épigénétique de l'expression de ZNF391.

Ellipticine

519-23-3sc-200878
sc-200878A
10 mg
50 mg
$142.00
$558.00
4
(1)

L'ellipticine est un agent d'intercalation de l'ADN, qui pourrait avoir un impact sur la régulation transcriptionnelle de ZNF391 et de ses voies associées.