ZBTB1 Antibody (E-4): sc-515076

ZBTB1 Antibody (E-4) is a mouse monoclonal IgG3 kappa light chain antibody that detects ZBTB1 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ZBTB1 antibody (E-4) is available as a non-conjugated format. ZBTB1, also known as zinc finger and BTB domain containing 1 or KIAA0997, is a crucial nuclear protein composed of 713 amino acids, featuring one BTB (POZ) domain and eight C2H2-type zinc fingers. This unique structure is significant as the BTB domain facilitates homodimerization and plays a vital role in transcriptional regulation by influencing chromatin structure and function. Multiple C2H2-type zinc fingers enhance ZBTB1′s ability to interact with DNA, thereby regulating gene expression. ZBTB1 is encoded on human chromosome 14, a region containing over 700 genes and accounting for nearly 3.5% of the human genome, underscoring ZBTB1′s importance in various biological processes. ZBTB1 (E-4) antibody enables researchers to explore this protein′s intricate roles in transcriptional regulation and potential implications in various diseases.

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ZBTB1 Antibody (E-4) References:

1. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.  |  Nagase, T., et al. 1999. DNA Res. 6: 63-70. PMID: 10231032
2. Discrimination of vanadium from zinc using gene profiling in human bronchial epithelial cells.  |  Li, Z., et al. 2005. Environ Health Perspect. 113: 1747-54. PMID: 16330358
3. The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila.  |  Zollman, S., et al. 1994. Proc Natl Acad Sci U S A. 91: 10717-21. PMID: 7938017
4. The POZ domain: a conserved protein-protein interaction motif.  |  Bardwell, VJ. and Treisman, R. 1994. Genes Dev. 8: 1664-77. PMID: 7958847
5. Crystal structure of the BTB domain from PLZF.  |  Ahmad, KF., et al. 1998. Proc Natl Acad Sci U S A. 95: 12123-8. PMID: 9770450

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ZBTB1 Antibody (E-4) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ZBTB1 Antibody (E-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ZBTB1 Antibody (E-4) Specifications

Alternate Product Name: ZBTB1

Product Clone Name: E-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 10-28

Epitope Target: ZBTB1

Epitope Species: human

Product Reactivity/Detection: ZBTB1

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ZBTB1 Antibody (E-4): P: Blocking Peptide