UBN-1 Antibody (UBN1G12): sc-81420
- UBN-1 Antibody (UBN1G12) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to an internal region of UBN-1 of human origin
- recommended for detection of UBN-1 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for UBN-1 Antibody (UBN1G12). This work is in progress.
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UBN-1 Antibody (UBN1G12) is a mouse monoclonal IgG1 antibody that detects UBN-1 in human samples through western blotting (WB) and immunoprecipitation (IP) applications. UBN-1, also known as ubinuclein, plays a crucial role in the regulation of gene expression and cellular processes by interacting with the EBV BZLF1 early gene product, EB1. This interaction is particularly significant as UBN-1 modulates the reactivation of Epstein-Barr virus (EBV) infection, which is a major concern in patients with compromised immune systems, such as those with AIDS. UBN-1 is predominantly located in the nucleus of human epidermal cells, where UBN-1′s amino terminus contains a nuclear localization signal that facilitates transport into the nucleus. The central domain of UBN-1 is essential for interaction with the DNA-binding domain of EB1, highlighting UBN-1′s importance in the viral life cycle and potential implications for therapeutic interventions in EBV-associated lymphoproliferative disorders. Anti-UBN-1 antibody (UBN1G12) enables researchers to gain valuable insights into the molecular mechanisms underlying EBV reactivation and its impact on human health.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
UBN-1 Antibody (UBN1G12) | sc-81420 | 100 µg/ml | $339.00 |