Troponin T-C Antibody (7e7): sc-52289
- Troponin T-C Antibody (7e7) is a mouse monoclonal IgG provided at 100 µg/ml
- raised against full length human cardiac troponin T
- recommended for detection of cardiac muscle troponin T of human origin by WB, IP and ELISA
- See Troponin T-C (CT3): sc-20025 for Troponin T-C antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Troponin T-C Antibody (7e7). This work is in progress.
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Troponin T-C Antibody (7e7) is a mouse monoclonal IgG antibody that detects Troponin T in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Troponin T plays a critical role in the regulation of muscle contraction by serving as a link between the troponin complex and the actin filaments in muscle cells. Anti-Troponin T antibody (7e7) helps researchers study specific domains that allow binding to tropomyosin, stabilizing the thin filament and facilitating the contraction process. Troponin T exists in different isoforms, which are expressed in various muscle types, allowing for specialized functions in cardiac and skeletal muscle contraction. Post-translational modifications, such as phosphorylation, influence Troponin T′s interaction with other proteins and overall function in muscle physiology. Anti-Troponin T antibody (7e7) serves as an invaluable tool for researchers studying muscle biology, cardiac function, and related pathologies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Troponin T-C Antibody (7e7) References:
- Drug-Induced Rhabdomyolysis with Elevated Cardiac Troponin T. | Egholm, G. and Pareek, M. 2015. Case Rep Med. 2015: 270204. PMID: 26557852
- High-sensitivity cardiac troponin T in geriatric inpatients. | Zhang, SJ., et al. 2016. Arch Gerontol Geriatr. 65: 111-5. PMID: 27017416
- Thrombin-Mediated Degradation of Human Cardiac Troponin T. | Katrukha, IA., et al. 2017. Clin Chem. 63: 1094-1100. PMID: 28428352
- Using High-Sensitivity Cardiac Troponin T for Acute Cardiac Care. | Sandoval, Y. and Jaffe, AS. 2017. Am J Med. 130: 1358-1365.e1. PMID: 28843652
- Diagnostic utility of cardiac troponin T level in patients with cardiac amyloidosis. | Takashio, S., et al. 2018. ESC Heart Fail. 5: 27-35. PMID: 28869340
- Stepwise C-Terminal Truncation of Cardiac Troponin T Alters Function at Low and Saturating Ca2. | Johnson, D., et al. 2018. Biophys J. 115: 702-712. PMID: 30057009
- Biotin and high-sensitivity cardiac troponin T assay. | Schrapp, A., et al. 2018. Biochem Med (Zagreb). 28: 030901. PMID: 30429682
- Inconsistent Findings of Cardiac Troponin T and I in Clinical Routine Diagnostics: Factors of Influence. | Eidizadeh, A., et al. 2021. J Clin Med. 10: PMID: 34300313
- Stress-induced cardiac troponin T, S100B and estradiol responses in defensive copers: The SABPA study. | Myburgh-Jacobsz, CE., et al. 2022. Int J Psychophysiol. 177: 159-170. PMID: 35577153
- Cardiac troponin T as a serum biomarker of respiratory impairment in amyotrophic lateral sclerosis. | Koch, T., et al. 2024. Ann Clin Transl Neurol. 11: 2063-2072. PMID: 38923228
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Troponin T-C Antibody (7e7) | sc-52289 | 100 µg/ml | $322.00 |