RAP55 Antibody (G-7): sc-390084
- RAP55 Antibody (G-7) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 41-75 near the N-terminus of RAP55 of human origin
- recommended for detection of RAP55 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, porcine and avian
- m-IgG2b BP-HRP is the preferred secondary detection reagent for RAP55 Antibody (G-7) for WB applications. This reagent is now offered in a bundle with RAP55 Antibody (G-7) (see ordering information below).
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SEE ALSO...
RAP55 Antibody (G-7) is a mouse monoclonal IgG2b antibody that detects RAP55 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RAP55, also known as LSM14A, is a 463 amino acid protein that plays a crucial role in RNA metabolism and is essential for the formation of processing bodies (P-bodies), which are involved in mRNA decay and storage. The protein contains a FFD-TFG box domain and features an Sm-like motif, which is vital for interaction with other proteins in the tri-snRNP complex, a key component in pre-mRNA splicing. Notably, RAP55 undergoes phosphorylation in response to DNA damage, likely mediated by ATM or ATR kinases, highlighting involvement in cellular stress responses. The gene encoding RAP55 is conserved across a wide range of species, including chimpanzees, dogs, and various model organisms, and is located on human chromosome 19q13.11. Anti-RAP55 antibody (G-7) serves as an invaluable tool for researchers studying RNA processing and cellular response to DNA damage, providing insights into molecular mechanisms underlying gene regulation and stability.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RAP55 Antibody (G-7) | sc-390084 | 200 µg/ml | $322.00 | |||
RAP55 Antibody (G-7): m-IgG2b BP-HRP Bundle | sc-548616 | 200 µg Ab; 10 µg BP | $361.00 | |||
RAP55 (G-7) Neutralizing Peptide | sc-390084 P | 100 µg/0.5 ml | $69.00 |