Rad51 Antibody (G-5): sc-133089
- Rad51 Antibody (G-5) is a mouse monoclonal IgG2a κ, cited in 5 publications, provided at 200 µg/ml
- raised against amino acids 1-180 mapping at the N-terminus of Rad51 of Saccharomyces cerevisiae origin
- Anti-Rad51 Antibody (G-5) is recommended for detection of Rad51 of y and human origin by WB, IP, IF and ELISA
- Anti-Rad51 Antibody (G-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Rad51 Antibody (G-5) for WB applications. These reagents are now offered in bundles with Rad51 Antibody (G-5) (see ordering information below).
Rad51 Antibody (G-5) is a mouse monoclonal IgG2a kappa light chain antibody designed to target the N-terminal region (amino acids 1-180) of the Rad51 protein from Saccharomyces cerevisiae, effectively recognizing human Rad51 across various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Rad51, also called Reca and Rad51a, is a pivotal protein involved in the homologous recombination repair pathway, essential for the accurate repair of DNA double-strand breaks and maintenance of genomic stability. anti-Rad51 antibody (G-5) assembles into helical nucleoprotein filaments analogous to bacterial RecA protein, enabling homology search and strand invasion during DNA repair. This filament formation is critical for promoting homologous pairing and strand exchange, thereby preventing mutations and maintaining genome integrity. Rad51 (G-5) antibody includes an ATPase domain and specific DNA-binding regions that allow seamless interaction with other key proteins such as BRCA2 and Rad52, which are integral to DNA damage response and repair mechanisms. The precise structural configuration ensures interactions and activities are tightly regulated, making Rad51 indispensable for cellular defense against genetic instability and tumorigenesis. Available in both non-conjugated form and various conjugated forms including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, Rad51 (G-5) monoclonal antibody offers versatile solutions for researchers investigating DNA repair mechanisms, homologous recombination, cancer biology, and genomic integrity. By targeting structurally and functionally critical regions, anti-Rad51 antibody (G-5) facilitates detailed studies into molecular foundations of DNA repair processes, advancing our understanding of cellular responses to DNA damage and prevention of genomic instability.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rad51 Antibody (G-5) | sc-133089 | 200 µg/ml | $322.00 | |||
Rad51 Antibody (G-5): m-IgG Fc BP-HRP Bundle | sc-528746 | 200 µg Ab; 10 µg BP | $361.00 | |||
Rad51 Antibody (G-5): m-IgGκ BP-HRP Bundle | sc-521230 | 200 µg Ab, 40 µg BP | $361.00 | |||
Rad51 Antibody (G-5): m-IgG2a BP-HRP Bundle | sc-547156 | 200 µg Ab; 10 µg BP | $361.00 | |||
Rad51 Antibody (G-5) AC | sc-133089 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Rad51 Antibody (G-5) HRP | sc-133089 HRP | 200 µg/ml | $322.00 | |||
Rad51 Antibody (G-5) FITC | sc-133089 FITC | 200 µg/ml | $336.00 | |||
Rad51 Antibody (G-5) PE | sc-133089 PE | 200 µg/ml | $349.00 | |||
Rad51 Antibody (G-5) Alexa Fluor® 488 | sc-133089 AF488 | 200 µg/ml | $364.00 | |||
Rad51 Antibody (G-5) Alexa Fluor® 546 | sc-133089 AF546 | 200 µg/ml | $364.00 | |||
Rad51 Antibody (G-5) Alexa Fluor® 594 | sc-133089 AF594 | 200 µg/ml | $364.00 | |||
Rad51 Antibody (G-5) Alexa Fluor® 647 | sc-133089 AF647 | 200 µg/ml | $364.00 | |||
Rad51 Antibody (G-5) Alexa Fluor® 680 | sc-133089 AF680 | 200 µg/ml | $364.00 | |||
Rad51 Antibody (G-5) Alexa Fluor® 790 | sc-133089 AF790 | 200 µg/ml | $364.00 |