phytanoyl-Coenzyme A (triethylammonium salt) MF: C41H74N7O17P3S•3NH
MW: 1107.1

phytanoyl-Coenzyme A (triethylammonium salt)

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Peso Molecular: 1107.1
Fórmula Molecular: C41H74N7O17P3S•3NH
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
* En el Certificado de Análisis específico de lote, puede encontrar información específica (como el contenido en agua).

A saturated 20-carbon branched-chain fatty acid which can only be derived from dietary sources. Under normal conditions, phytanic acid is degraded via α-oxidation (oxidative decarboxylation) to produce pristanic acid, which then undergoes β-oxidation as part of the metabolism process. Degradation of phytanic acid is impaired in patients with peroxisomal disorders or diseases such as infantile phytanic acid storage disease or Refsum's disease.


References

1 Watkins, P.A., Howard, A.E., Mihalik, S.J. Phytanic acid must be activated to phytanoyl-CoA prior to its a-oxidation in rat liver peroxisomes. Biochem Biophys Acta 1214 288-294 (1994). 2 Watkins, P.A., Howard, A.E., Gould, S.J., et al. Phytanic acid activation in rat liver peroxisomes is catalyzed by long-chain acyl-CoA synthetase. J Lipid Res 37 2288-2295 (1996). 3 Wanders, R.J.A., Boltshauser, E., Steinmann, B., et al. Infantile phytanic acid storage disease, a disorder of peroxisome biogenesis: A case report. J Neurol Sci 98 1-11 (1990).

Estado de Materia :
Solid
ALMACENAMIENTO :
Store at -20° C
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.

Descargar SDS (MSDS)

CERTIFICADO DE ANÁLISIS

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